Why reverse transcriptase enzymes are having comparatively high error rates than other polymerases?

A. Because they are not having 3’-5’ proofreading exonucleolytic activity

B. Because they are not having 5’-3’ proofreading exonucleolytic activity

C. Because they are having slow rates of exonucleolytic activity

D. It is difficult to synthesize DNA from RNA

Explanation: Reverse transcriptase enzymes are not having proofreading exonuclease activity in 3’-5’ direction. Hence, when the synthesis is done in 5’-3’ direction, it is not checked in the 3’-5’ direction; thus, the inculcated errors won’t be removed.

Post a Comment

0 Comments